Srimoyee Mukherjee

This study shows CFIm25 regulates macrophage polarization by controlling AKT2 mRNA polyadenylation, promoting M1 traits and suppressing M2 features.

This study shows CFIm25 enhances macrophage antibacterial immunity against Salmonella by regulating alternative polyadenylation and boosting MAPK and NF-κB signaling.

The paper shows that alternative polyadenylation of CFIm25 mRNA removes PCBP1 binding during macrophage differentiation, increasing CFIm25 protein and promoting differentiation markers.

This study shows that CFIm25 promotes macrophage differentiation by enhancing alternative polyadenylation and activating the NF-κB pathway.

This study shows that macrophage differentiation involves changes in mRNA polyadenylation, poly(A) site usage, and sensitivity to CstF64, a cleavage/polyadenylation protein.