Sandro Galea

The paper develops a heterogeneous mediation analysis method to study DNA methylation's role in PTSD among African Americans, identifying subgroups and mediators linked to PTSD symptoms.

The paper examines how DNA methylation at NFATC1 CpG sites mediates the relationship between different trauma types and PTSD risk in a prospective study.

This study examines how neighborhood conditions relate to epigenetic aging using DNA methylation clocks in a sample of 158 individuals from the Detroit Neighborhood Health Study.

The paper uses machine learning to identify factors predicting prospective risk of post-traumatic stress symptoms, finding that prior PTSS, loneliness, and a specific DNA methylation site are key predictors.

This study identifies genetic variants associated with self-reported childhood maltreatment and finds significant genetic correlations with depressive symptoms.

The paper identifies sex-specific changes in monocyte proportions in males with PTSD using methylomic data, showing no such changes in females.

This study identifies ten novel methylation loci associated with PTSD through a meta-analysis of 1,896 cases and controls across ten cohorts, highlighting the AHRR locus and its link to kynurenine levels.

This study conducts the largest GWAS for PTSD, identifying 6 genome-wide significant loci in European and African ancestries and highlighting novel biological pathways.