Author

Pieter Leyssen

Rega Institute for Medical ResearchORCID 0000-0002-7537-1688Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Microbiology· 2 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 3 Approach:experimental assay· 3 Organism:human· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:host-pathogen & immune response· 1 Assay:imaging· 1 Assay:organoid / primary culture· 1 Approach:statistical model· 1

Frequent Co-Authors

Johan H. NeytsiD· 3 shared Steven De JongheiD· 2 shared Aditi AgrawaliD· 1 shared Amrita OjhaiD· 1 shared Andrea R. BeccariiD· 1 shared Andrea ZalianiiD· 1 shared Angela CoronaiD· 1 shared Antti PosoiD· 1 shared

Activity by Year

2021-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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Curved chords = mutual co-authorship

3 shared papersMicrobiology

Johan H. NeytsORCID

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Author profile →

3 papers

Recent·Most cited

MicrobiologybioRxivPreprintOct 28, 2025

A high-throughput cell-based platform for Rhinovirus C research and antiviral drug discovery.

Heyrhyoung Lyoo, Yeranddy Aguiar Alpizar, Céline Sablon…·Hendrik Jan Thibaut

This paper develops a high-throughput imaging platform for RV-C research and antiviral drug discovery, identifying inhibitors through compound screening.

DOI 10.1101/2025.10.28.680218

humanimaging

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MicrobiologyNature CommunicationsPeer-reviewedJul 10, 2025

PIP4K2C inhibition reverses autophagic flux impairment induced by SARS-CoV-2

Marwah Karim, Manjari Mishra, Chieh‐Wen Lo…·Shirit Einav

RMC-113 inhibits PIP4K2C and PIKfyve, reversing SARS-CoV-2-induced autophagic flux impairment and showing antiviral effects.

19 citationstop 1%

humanorganoid / primary culture

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Molecular BiologyACS Pharmacology & Translational SciencePeer-reviewedMar 11, 2021

Identification of inhibitors of SARS-CoV-2 3CL-Pro enzymatic activity using a small molecule in-vitro repurposing screen

Maria Kuzikov, Elisa Costanzi, Jeanette Reinshagen…·Andrea Zaliani

The paper identifies 62 new inhibitors of SARS-CoV-2 3CL-Pro through a compound repurposing screen and validates their activity using X-ray crystallography.

159 citationstop 1%

experimental assaydrug response / drug discovery

𝕏 PostBluesky