Panayiota Poirazi

The paper investigates how dendritic turnover zones in the secondary motor cortex support rule switching without expanding the cortical engram by analyzing spine dynamics and modeling synaptic reorganization.

The paper develops an analytical framework to understand how inhibition affects neuronal computation across dendritic compartments, revealing a unified law that explains inhibitory leverage in active dendrites.

DendroTweaks provides an interactive toolbox for exploring and validating detailed biophysical neuronal models with active dendrites.

This study shows that mice do not uniformly express defensive behaviors when exposed to predators, instead showing context-dependent and variable responses.

The paper shows that clustered excitatory synapses on dendrites improve place field encoding efficiency in hippocampal neurons compared to randomized distributions.

The paper uses experimental and computational methods to show that spontaneous network activity patterns predict the effects of targeted stimulation in hippocampal neuronal cultures.

The paper identifies distinct dendritic integration strategies in two types of cortical interneurons that lead to different temporal dynamics of inhibition.

The paper models how apical and basal dendritic trees of L2/3 V1 pyramidal neurons synergistically contribute to somatic action potential generation in response to visual stimuli.

This study shows that synaptic turnover improves learning efficiency in spiking neural networks, especially under resource constraints.

The paper introduces Dendrify, a Python framework that generates simplified yet biologically relevant neuron models with dendritic properties for spiking neural networks.

This study shows that LEC inputs drive dendritic spikes in CA1 pyramidal neurons via a disinhibitory VIP interneuron circuit, revealing a mechanism for context-specific hippocampal coding.

The paper identifies a locus coeruleus-dorsal CA1 dopaminergic circuit that modulates memory linking without affecting memory formation.

The paper shows that dendritic plasticity in the retrosplenial cortex links memories by allocating spine clusters to the same dendritic segments for temporally close memories.

Hippocampal pyramidal cells show branch-specific tuning for different place fields, and their coupling to their soma changes with experience of an environment.

The paper investigates how apical and basal dendrites of L2/3 pyramidal neurons in mouse V1 contribute to orientation encoding, finding that orientation tuning is robust to dendritic ablation.

The paper models PFC circuit mechanisms to show how structured connectivity and NMDA non-linearities enable flexible encoding of multiple memoranda through dynamic neuronal assemblies.

The paper challenges the point neuron dogma by showing FS basket cells use nonlinear dendritic computations, modeled as a 2-stage ANN, to explain somatic firing variability.

This study investigates spatial coding and neural synchronization in epilepsy using in vivo calcium imaging and network modeling, finding impaired spatial processing and desynchronized firing in epileptic mice.

This study uses a computational model to show that dendrites of DG granule cells enhance pattern separation by maintaining sparsity, and their atrophy impairs this function.