Zhuogui Lei

Astrocytic L-lactate signaling in the anterior cingulate cortex is essential for schema memory and neuronal mitochondrial biogenesis

This study shows that astrocytic Gi signaling in the ACC reduces L-lactate levels, impairing schema memory and neuronal mitochondrial biogenesis in rats, with L-lactate rescue reversing these effects.

Dopamine modulates visual threat processing in the superior colliculus via D2 receptors

This study shows that D2 dopamine receptors in the superior colliculus modulate defensive behaviors to visual threats, with optogenetic activation promoting defensive responses and chemogenetic inhibition reducing them.

Glutamatergic and GABAergic neuronal populations in thedorsolateral Periacqueductual Gray have differentfunctional roles in fear conditioning

The paper investigates the functional roles of glutamatergic and GABAergic neuronal populations in the dorsolateral periacqueductal gray during fear conditioning, finding that only glutamatergic neurons persist in responding to conditioned stimuli during retrieval.

Characterization of glutamatergic VTA neural population responses to aversive and rewarding conditioning in freely-moving mice

This study investigates how glutamatergic VTA neurons respond to aversive and rewarding conditioning in mice, revealing distinct patterns during conditioning and retrieval phases.