Author

Antti Kukkula

University of TurkuORCID 0000-0002-7580-4455Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 2 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:drug response / drug discovery· 1 Assay:proteomics· 1

Frequent Co-Authors

Maria SundvalliD· 2 shared Saiganesh SriramaniD· 2 shared Verneri VirtaneniD· 2 shared Anne RokkaiD· 1 shared Anni Lumiainen· 1 shared Daniel BexelliD· 1 shared Gun WestiD· 1 shared Ilkka PaateroiD· 1 shared

Activity by Year

2024-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

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2 shared papersCancer Biology

Maria SundvallORCID

Mutual co-authors in cluster

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2 papers

Recent·Most cited

SUMOylation is a Therapeutic Vulnerability in High-risk Neuroblastoma

Antti Kukkula, Saiganesh Sriraman, Verneri Virtanen, Sara LM Kuusela, Lara Kozina Bubnic, Ilkka Paatero, Vilja M. Pietiäinen, Daniel Bexell, Maria Sundvall

This study identifies SUMOylation as a therapeutic target in high-risk neuroblastoma, showing that SUMO pathway inhibitors like TAK-981 reduce tumor growth and are effective in combination with other therapies.

bioRxiv · Sep 10, 2026 · PreprintCancer Biology

Functionality of BRCA1 supports the survival of prostate cancer cells during the development of castration resistance

Saiganesh Sriraman, Verneri Virtanen, Antti Kukkula, Mervi Toriseva, Anne Rokka, Anni Lumiainen, Johanna K. Ahlskog, Gun West, Matti H. POUTANEN, Pekka Taimen, Maria Sundvall

This study shows that BRCA1 supports prostate cancer cell survival during castration resistance by modulating mTOR signaling and NRF2-mediated antioxidant processes.

bioRxiv · Jun 19, 2024 · PreprintCancer Biology