Wenxin Zhang

Identification and characterization of the de novo methyltransferases for eukaryotic N6-methyladenine (6mA)

The paper identifies TET1 and TET2 as de novo methyltransferases responsible for 6mA methylation in Tetrahymena thermophila during sexual reproduction, showing their essential role in genome-wide methylation and gene expression.

Robust Benchmark Structural Variant Calls of An Asian Using the State-of-Art Long Fragment Sequencing Technologies

The paper establishes high-confidence structural variant calls in an Asian individual using long-read sequencing technologies and validates them through PCR and Sanger sequencing.

An integrated Asian human SNV and indel benchmark combining multiple sequencing methods

The paper constructs a high-confidence Asian variant benchmark using multiple sequencing methods and identifies novel variants in challenging regions.