Author

Haicheng Li

Qingdao National Laboratory for Marine Science and TechnologyORCID 0000-0002-7268-6967Unclaimed ORCID profile · follow to get notified of new preprints

Additional preprints under this name without ORCID

Haicheng Li1 paper · Ocean University of China

Biology Disciplines

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Bioinformatics· 1 Genetics· 1 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Assay:DNA methylation· 2 Approach:experimental assay· 2 Research Focus:gene regulatory network inference· 2 Approach:statistical model· 2 Research Focus:variant calling· 2 Assay:ChIP-seq· 1 Research Focus:differential expression· 1 Assay:long-read sequencing· 1

Frequent Co-Authors

Junhua NiuiD· 2 shared Aili JuiD· 1 shared Fan Wei· 1 shared Fei YeiD· 1 shared Hongzhen Jiang· 1 shared Jiachen ZhangiD· 1 shared Jinghan Diao· 1 shared Kensuke Kataoka· 1 shared

Activity by Year

2024-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 17 mutual co-author links

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2 shared papersBioinformatics

Junhua NiuORCID

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3 papers

Recent·Most cited

Bromodomain protein IBD1 bridges histone acetylation and H2A.Z deposition to fine-tune transcription and prevent hyperactivation in Tetrahymena thermophila

Zhe Zhang, Haicheng Li, Fan Wei, Aili Ju, Hongzhen Jiang, Fei Ye, Yongqiang Liu, Shan Gao, Yuan‐Yuan Wang

This study identifies IBD1 as a bridge between histone acetylation and H2A.Z deposition, showing its role in maintaining transcriptional homeostasis by preventing hyperactivation.

bioRxiv · Jun 29, 2025 · PreprintGenetics

SMAC: identifying DNA N6-methyladenine (6mA) at the single-molecule level using SMRT CCS data

Haicheng Li, Junhua Niu, Yalan Sheng, Yifan Liu, Shan Gao

SMAC detects DNA N6-methyladenine at the single-molecule level using SMRT CCS data, improving accuracy over existing methods.

Briefings in Bioinformatics · Mar 1, 2025Peer-reviewedBioinformatics

Identification and characterization of the de novo methyltransferases for eukaryotic N6-methyladenine (6mA)

Ting Cheng, Jiachen Zhang, Haicheng Li, Jinghan Diao, Wenxin Zhang, Junhua Niu, Kensuke Kataoka, Shan Gao

The paper identifies TET1 and TET2 as de novo methyltransferases responsible for 6mA methylation in Tetrahymena thermophila during sexual reproduction, showing their essential role in genome-wide methylation and gene expression.

bioRxiv · Mar 25, 2024 · PreprintMolecular Biology