Author

Ian L. Tschang

State University of New YorkORCID 0000-0002-7599-1668Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:mouse· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Assay:proteomics· 1

Frequent Co-Authors

Annalisa ScimemiiD· 2 shared Gabrielle C. ToddiD· 2 shared Maurice A. PetroccioneiD· 2 shared Nurat AffinnihiD· 2 shared Patrick H. WehrleiD· 2 shared Anthony K. ManningiD· 1 shared Brianna R. TsakhiD· 1 shared David G. CookiD· 1 shared

Activity by Year

2023-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 36 mutual co-author links

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2 shared papersNeuroscience

Annalisa ScimemiORCID

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Author profile →

3 papers

Recent·Most cited

TRAP seq in 3D Angiogenesis Assays Reveals a Distinct Endothelial Translatome Associated with Early and Late Stages of Morphogenesis.

Samantha King, Q. Li, Ian L. Tschang, Ekta Singh, Ramon Bossardi Ramos, Kevin M. Pumiglia

The paper uses TRAP seq in 3D angiogenesis assays to identify endothelial-specific gene expression changes during early and late stages of morphogenesis.

Scientific Reports · Sep 29, 2025Peer-reviewedCell Biology

An increased excitation and inhibition onto CA1 pyramidal cells sets the path to Alzheimer's disease

Patrick H. Wehrle, Travis J. Rathwell, Maurice A. Petroccione, Ethan D. Caiazza, Anthony K. Manning, Leonardo Frasson dos Reis, Gabrielle C. Todd, Nurat Affinnih, Saad Ahmad, Hasan Mehdi, Ian L. Tschang, Umair Hassan, Brianna R. Tsakh, Marisol C. Lauffer, Paul A. Rosenberg, , Annalisa Scimemi

This study shows that Aβ42 accumulation increases excitatory and inhibitory synaptic transmission onto CA1 pyramidal cells and GLT-1 expression, which mediates its effects on cognition.

bioRxiv · May 27, 2025 · PreprintNeuroscience

Neuronal glutamate transporters control reciprocal inhibition and gain modulation in D1 medium spiny neurons

Maurice A. Petroccione, Lianna Y. D’Brant, Nurat Affinnih, Patrick H. Wehrle, Gabrielle C. Todd, Shergil Zahid, Haley E. Chesbro, Ian L. Tschang, Annalisa Scimemi

This study shows that neuronal glutamate transporter EAAC1 modulates synaptic excitation and lateral inhibition in D1-MSNs, affecting behavior through gain modulation and reduced firing sensitivity.

eLife · Jul 12, 2023Peer-reviewedNeuroscience