Author

Xavier Descombes

Centre National de la Recherche ScientifiqueORCID 0000-0002-7611-6021Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cell Biology· 1 Neuroscience· 1

Signature Assays, Organisms & Methods

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Assay:imaging· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell type annotation· 1 Research Focus:clustering· 1 Approach:experimental assay· 1 Organism:human· 1 Approach:machine learning (classical)· 1 Organism:mouse· 1

Frequent Co-Authors

Alain CorinusiD· 1 shared Anne-Sophie GayiD· 1 shared Carole RovèreiD· 1 shared Céline CanselliD· 1 shared Christelle Boscagli· 1 shared Clara SancheziD· 1 shared Delphine DebayleiD· 1 shared Éric DebreuveiD· 1 shared

Activity by Year

2025-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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1 shared paperCell Biology

Alain CorinusORCID

Mutual co-authors in cluster

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2 papers

Recent·Most cited

Cell BiologyMatrix BiologyPeer-reviewedDec 2, 2025

Human mammary 3D spheroid models uncover the role of filopodia in breaching the basement membrane to facilitate invasion

Alain Corinus, Sophie Abélanet, Julia Dubreuil…·Frédéric Luton

The paper uses 3D spheroid models to show filopodia-like protrusions help breast cancer cells invade by widening basement membrane pores.

5 citations

𝕏 PostBluesky

NeuroscienceMethodsPeer-reviewedFeb 26, 2025

Computational detection, characterization, and clustering of microglial cells in a mouse model of fat-induced postprandial hypothalamic inflammation

Clara Sanchez, Morgane Nadal, Céline Cansell…·Éric Debreuve

This paper introduces an automated algorithm to detect and cluster microglial cells in mouse hypothalamic tissue, revealing morphological subpopulations affected by high-fat diet.

DOI 10.1016/j.ymeth.2025.02.008

𝕏 PostBluesky