Delphine Debayle

This study shows that deleting ferritin heavy chain in medulloblastoma cells limits tumor growth by promoting iron-dependent stress and sensitizing cells to iron toxicity.

This study shows that ether lipid remodeling during neuronal differentiation prevents ferroptosis by balancing pro- and anti-ferroptotic effects through vinyl ether bonds.

The paper uses 3D spheroid models to show filopodia-like protrusions help breast cancer cells invade by widening basement membrane pores.

This study shows that short- and medium-chain fatty acids are preferentially oxidized within adipocytes rather than released, due to their distinct storage and mobilization dynamics compared to long-chain fatty acids.

This study characterizes large extracellular vesicles containing mitochondria (EVMs) from Alzheimer's Disease cells, showing they carry pathological mitochondrial dysfunction and spread it to recipient cells.

This study shows that high-fat diet-induced obesity in mice increases heat pain hypersensitivity via lysophosphatidylcholine activation of ASIC3 channels in dorsal root ganglia neurons.

This paper introduces GENF, a gene disruption strategy that avoids clone isolation, enabling reliable lipidomics analysis and revealing lipid co-regulatory networks.

The paper investigates how high-fat diet exposure increases hypothalamic inflammation and glial cell activity in mice, linking it to potential obesity risk.