Serum C-terminal agrin fragment as a biomarker of age-related neuromuscular decline in men: influence of physical activity
Rami Hammad, Vincent Marcangeli, Marina Cefis, Rémi Chaney, Krystel Desjardins, Jordan Granet, Pierrette Gaudreau, Richard Robitaille, José A. Morais, Mylène Aubertin‐Leheudre, Marc Bélanger, Gilles Gouspillou
This study finds that serum C-terminal agrin fragment (CAF) increases with age and is linked to neuromuscular decline and reduced physical function, with physical activity mitigating these effects in older men.
bioRxiv · Sep 7, 2026 · PreprintPhysiology