BiochemistrybioRxivPreprint
SF3B1 Phosphorylation Prompts U2AF2 Dissociation for Widespread Control of pre-mRNA Splicing
Christopher L. Kirchhoff, Hannah R. Powell, Justin W. Galardi…·Clara L. Kielkopf
This study shows SF3B1 phosphorylation reduces its binding to U2AF2, enabling widespread control of pre-mRNA splicing by promoting U2AF2 dissociation.
DOI 10.64898/2026.01.19.700466