Author

Jason Talkish

University of California, Santa CruzORCID 0000-0002-0260-3345Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

Click to filter author papers

Molecular Biology· 3 Genomics· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Organism:yeast· 4 Approach:experimental assay· 3 Assay:DNA methylation· 1 Research Focus:gene regulatory network inference· 1 Assay:long-read sequencing· 1 Approach:statistical model· 1 Assay:whole-genome sequencing· 1

Frequent Co-Authors

Haller IgeliD· 4 shared Manuel AresiD· 4 shared John Paul DonohueiD· 2 shared Oarteze HunteriD· 2 shared Sol J. KatzmaniD· 2 shared Alejandra Durán· 1 shared Andrew D. BaileyiD· 1 shared Asako Tan· 1 shared

Activity by Year

2019-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 27 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

4 shared papersMolecular Biology

Haller IgelORCID

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Molecular BiologyRNAPeer-reviewedNov 28, 2023

Broad variation in response of individual introns to splicing inhibitors in a humanized yeast strain

Oarteze Hunter, Jason Talkish, Jen Quick-Cleveland…·Manuel Ares

The paper studies how different introns respond to splicing inhibitors in a humanized yeast strain, revealing intron-specific sensitivity and the impact of BP sequence variation.

9 citations

yeastexperimental assay

𝕏 PostBluesky

Molecular BiologyeLifePeer-reviewedApr 6, 2022

Concerted modification of nucleotides at functional centers of the ribosome revealed by single-molecule RNA modification profiling

Andrew D. Bailey, Jason Talkish, Hongxu Ding…·Manuel Ares

The paper develops a method to profile single-molecule RNA modifications in yeast rRNA, revealing concerted modifications at functional centers and subpopulation changes in ribosome biogenesis.

46 citations

yeastlong-read sequencing

𝕏 PostBluesky

GenomicsPLoS GeneticsPeer-reviewedAug 22, 2019

Rapidly evolving protointrons in Saccharomyces genomes revealed by a hungry spliceosome

Jason Talkish, Haller Igel, Rhonda Perriman…·Manuel Ares

The paper identifies over 150 new spliced regions in yeast genomes, termed protointrons, which are not conserved and may represent early stages of intron evolution.

25 citations

yeastDNA methylation

𝕏 PostBluesky

Molecular BiologyRNAPeer-reviewedMay 20, 2019

Cus2 enforces the first ATP-dependent step of splicing by binding to yeast SF3b1 through a UHM-ULM interaction

Jason Talkish, Haller Igel, Oarteze Hunter…·Manuel Ares

The paper identifies Cus2's role in splicing by binding to SF3b1 via a UHM-ULM interaction and shows its ATP-dependent removal is essential for pre-spliceosome formation.

30 citations

yeastexperimental assay

𝕏 PostBluesky