Author

Uche N. Medoh

Aligning Science Across Parkinson'sORCID 0000-0002-7670-4093Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Biochemistry· 1 Cell Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:differential expression· 2 Organism:mouse· 2 Research Focus:cell type annotation· 1 Approach:experimental assay· 1 Assay:metabolomics· 1 Assay:proteomics· 1 Approach:statistical model· 1

Frequent Co-Authors

Eshaan S. RawatiD· 2 shared Kwamina NyameiD· 2 shared Monther Abu-RemailehiD· 2 shared Wentao DongiD· 2 shared Alessandro OriiD· 1 shared Ali GhoochaniiD· 1 shared Alina IsakovaiD· 1 shared Caio C. BoniniD· 1 shared

Activity by Year

2026-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 40 mutual co-author links

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2 shared papersBiochemistry

Eshaan S. RawatORCID

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

Robust analytical methods for bis(monoacylglycero)phosphate profiling in health and disease

Wentao Dong, Kwamina Nyame, Eshaan S. Rawat, Uche N. Medoh, Jian Xiong, Caio C. Bonin, Hisham N. Alsohybe, H LIU, Sara Gomes, Tammy Shalit, Marianna Arnold, F. Hsieh, Esther M. Sammler, Monther Abu-Remaileh

This study develops LC/MS methods for accurate BMP profiling, using CLN5 knockout cells to distinguish BMP from PG and introduce BMPII and BMPES metrics.

Nature Protocols · Jun 10, 2026Peer-reviewedBiochemistry

Cell-Type Resolved Protein Atlas of Brain Lysosomes Identifies SLC45A1-Associated Disease as a Lysosomal Disorder

Ali Ghoochani, Julia C. Heiby, Eshaan S. Rawat, Uche N. Medoh, Domenico Di Fraia, Wentao Dong, Marc Gastou, Mohit Rastogi, Vincent Hernandez, Kwamina Nyame, Nouf N. Laqtom, William Durso, Christina Valkova, Alina Isakova, Christoph Kaether, , Monther Abu-Remaileh

The paper creates a cell-type-specific lysosome protein atlas in the brain, identifies SLC45A1 as a neuron-specific lysosomal protein, and shows its role in lysosomal function and neurodegeneration.

Cell · Jan 22, 2026Peer-reviewedCell Biology