Author

Christina Valkova

Leibniz Institute on Aging - Fritz Lipmann Institute (FLI)

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 2 Neuroscience· 1

Signature Assays, Organisms & Methods

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Organism:mouse· 3 Assay:proteomics· 3 Research Focus:differential expression· 2 Approach:experimental assay· 2 Research Focus:cell type annotation· 1 Research Focus:development & morphogenesis· 1 Approach:statistical model· 1

Frequent Co-Authors

Christoph KaetheriD· 3 shared Alessandro Ori‬‬iD· 2 shared Domenico Di FraiaiD· 2 shared William DursoiD· 2 shared Alexander Gloria· 1 shared Ali GhoochaniiD· 1 shared Alina IsakovaiD· 1 shared Christian FrankeiD· 1 shared

Activity by Year

2026-2026 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 31 mutual co-author links

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3 shared papersCell Biology

Christoph KaetherORCID

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Author profile →

3 papers

Recent·Most cited

Distinct Effects of Aging and Klotho Deletion on the Choroid Plexus

Zahra Fanaei‐Kahrani, Tushar Patel, Christina Valkova, Alexander Gloria, Justine Wagner, Heike Heuer, Markus Schwaninger, Steve Hoffmann, Reinhard Bauer, Christoph Kaether

This study examines how aging and Klotho deletion affect choroid plexus structure and function, finding that Klotho deficiency increases age-related calcification in specific regions.

GeroScience · Mar 25, 2026Peer-reviewedNeuroscience

The microcephaly-associated protein YIPF5 differentially regulates ER-export

Francesca Bruno, Mihaela Anitei, Domenico Di Fraia, William Durso, Therese Dau, Emilio Cirri, Mara Sannai, Christina Valkova, Julija Maldutyte, Elizabeth A. Miller, Ignacio Rubio, Vera Garloff, Noortje Kersten, Ginny G. Farı́as, Alessandro Ori‬‬, , Christoph Kaether

This study shows YIPF5 regulates ER export of specific proteins, and its disruption causes neuronal migration defects and microcephaly.

iScience · Jan 27, 2026Peer-reviewedCell Biology

Cell-Type Resolved Protein Atlas of Brain Lysosomes Identifies SLC45A1-Associated Disease as a Lysosomal Disorder

Ali Ghoochani, Julia C. Heiby, Eshaan S. Rawat, Uche N. Medoh, Domenico Di Fraia, Wentao Dong, Marc Gastou, Mohit Rastogi, Vincent Hernandez, Kwamina Nyame, Nouf N. Laqtom, William Durso, Christina Valkova, Alina Isakova, Christoph Kaether, , Monther Abu-Remaileh

The paper creates a cell-type-specific lysosome protein atlas in the brain, identifies SLC45A1 as a neuron-specific lysosomal protein, and shows its role in lysosomal function and neurodegeneration.

Cell · Jan 22, 2026Peer-reviewedCell Biology