Julia C. Heiby

Mitochondrial degradation of metallothionein enables local zinc mobilization during zinc limitation

The paper identifies a mitochondrial degradation pathway for metallothionein that releases zinc during zinc limitation, maintaining metabolic homeostasis.

Cell-Type Resolved Protein Atlas of Brain Lysosomes Identifies SLC45A1-Associated Disease as a Lysosomal Disorder

The paper creates a cell-type-specific lysosome protein atlas in the brain, identifies SLC45A1 as a neuron-specific lysosomal protein, and shows its role in lysosomal function and neurodegeneration.

NanTex enables computational multiplexing and phenotyping of organelles across super-resolution modalities

NanTex enables multiplexing and phenotyping of organelles using nanotexture descriptors from single-channel super-resolution microscopy data across multiple modalities.