Silvia Martı́n-Puig

This study shows that loss of HIF1α in smooth muscle cells in atherosclerosis leads to oxidative stress, increased SMC proliferation, and plaque expansion.

This study shows that activating HIF2 causes vascular remodeling, inflammation, and coronary issues similar to Kawasaki disease, using a new mouse model and human tissue analysis.

This study shows that HIF2 signaling in the Wt1 lineage prevents cardiomegaly and pulmonary remodeling during chronic hypoxia but causes microvascular instability and cardiac dysfunction when absent.

The paper investigates the effects of HIF1 deletion in cardiac progenitors, finding that it leads to impaired glycolysis and activation of an amino acid metabolic program without affecting heart development or function.

This study investigates the effects of HIF1α deletion in cardiac progenitors during heart development, finding that HIF1 is dispensable for cardiac growth and reveals metabolic reprogramming toward amino acid utilization.