Beatriz Escobar

Vascular HIF2 signaling prevents cardiomegaly, alveolar congestion and capillary remodeling during chronic hypoxia

This study shows that HIF2 signaling in the Wt1 lineage prevents cardiomegaly and pulmonary remodeling during chronic hypoxia but causes microvascular instability and cardiac dysfunction when absent.

Activation of amino acid metabolic program in response to impaired glycolysis in cardiac HIF1 deficient mice

The paper investigates the effects of HIF1 deletion in cardiac progenitors, finding that it leads to impaired glycolysis and activation of an amino acid metabolic program without affecting heart development or function.

Metabolic reprogramming from glycolysis to amino acid utilization in cardiac HIF1α deficient mice.

This study investigates the effects of HIF1α deletion in cardiac progenitors during heart development, finding that HIF1 is dispensable for cardiac growth and reveals metabolic reprogramming toward amino acid utilization.