Deadenylation rate is not a major determinant of RNA degradation in yeast
Léna Audebert, Frank Feuerbach, Laurence Decourty, Abdelkader Namane, Emmanuelle Permal, Gwenaël Badis, Cosmin Saveanu
The paper shows that mRNA stability in yeast is determined by decapping speed, not deadenylation rate, with unstable mRNAs having rapid decapping and longer poly(A) tails.
bioRxiv · Jan 16, 2023 · PreprintMolecular Biology