Ran Xu

The paper investigates electrical signaling between mid-capillary pericytes and endothelial cells in the neurovascular unit, showing syncytial coupling and its role in transmitting seizure-associated signals without relying on VGCCs.

This paper maps mutation-defined cancer vulnerabilities across 22 cohorts, identifying OXPHOS addiction in CDKN2A-loss LUSC and highlighting drug repurposing opportunities using a machine learning framework.

This study shows NASPM inhibits NMDA receptors rather than CP-AMPARs in human brain tissue, challenging its use as a specific CP-AMPAR inhibitor and questioning its therapeutic potential.