Karen L Cunningham

Deep Neural Networks to Register and Annotate Cells in Moving and Deforming Nervous Systems

This paper introduces deep neural networks for aligning and annotating cells in moving nervous systems, achieving high accuracy in registration and cell type identification.

Molecular Logic of Synaptic Diversity Between Drosophila Tonic and Phasic Motoneurons

The paper identifies molecular pathways underlying synaptic diversity between Drosophila tonic and phasic motoneurons through single-cell RNA profiling and genetic analysis.

Loss of the extracellular matrix protein Perlecan disrupts axonal and synaptic stability during Drosophila development

This study shows that Perlecan is essential for maintaining axonal and synaptic stability in Drosophila motoneurons, with its loss causing axonal breakage and synaptic retraction.

Regulation of presynaptic Ca2+ channel abundance at active zones through a balance of delivery and turnover

The paper investigates how voltage-gated Ca2+ channel abundance at Drosophila active zones is regulated through delivery, turnover, and interactions with BRP and 2{delta}.

The decoy SNARE Tomosyn sets tonic versus phasic release properties and is required for homeostatic synaptic plasticity

The paper identifies Tomosyn as a regulator of synaptic release properties and homeostatic plasticity in Drosophila motoneurons.

Examining molecular determinants underlying heterogeneity of synaptic release probability using optical quantal imaging

The paper examines the molecular determinants of synaptic release probability heterogeneity using optical quantal imaging in Drosophila neuromuscular junctions.