Author

Wuyang Chen

City Of Hope National Medical CenterORCID 0000-0002-7746-4191Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cancer Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Organism:human· 1 Organism:mouse· 1 Assay:scRNA-seq· 1 Approach:statistical model· 1

Frequent Co-Authors

Behnam BadieiD· 1 shared Christine E. BrowniD· 1 shared Darya AlizadehiD· 1 shared Dominic J. Bellavari· 1 shared Heini M. NatriiD· 1 shared John David JeppsoniD· 1 shared Jonathan C. HibbardiD· 1 shared Joseph R. Pecoraro· 1 shared

Activity by Year

2026-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperCancer Biology

Behnam BadieORCID

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1 paper

Recent·Most cited

Therapeutic Targeting of the TGFβ Pathway Augments CAR T cell Efficacy in Glioblastoma

Darya Alizadeh, Robyn A. Wong, Madeleine S. Maker, Dominic J. Bellavari, Jonathan C. Hibbard, Heini M. Natri, Wuyang Chen, Min-Hsuan Chen, Xiwei Wu, Yate‐Ching Yuan, Joseph R. Pecoraro, John David Jeppson, Renate Starr, Zhiqiang Wang, Nicholas E. Banovich, , Christine E. Brown

This study shows that targeting the TGFβ pathway improves CAR T cell efficacy in glioblastoma by enhancing antitumor activity and modulating the tumor microenvironment.

bioRxiv · Oct 28, 2026 · PreprintCancer Biology