Author

Christopher A. Lavender

National Institutes of HealthORCID 0000-0002-7762-1089Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Bioinformatics· 1 Genomics· 1 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Assay:ChIP-seq· 2 Research Focus:differential expression· 2 Approach:experimental assay· 2 Research Focus:gene regulatory network inference· 2 Organism:human· 2 Research Focus:variant calling· 2 Assay:bulk RNA-seq· 1 Approach:deep learning· 1

Frequent Co-Authors

Karen AdelmaniD· 2 shared Telmo HenriquesiD· 2 shared A. Gregory MateraiD· 1 shared Adam BurkholderiD· 1 shared Alexandr A. KalininiD· 1 shared Amr M. AlexandariiD· 1 shared Andrew OldfieldiD· 1 shared Anne Elizabeth CarpenteriD· 1 shared

Activity by Year

2017-2019 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 18 mutual co-author links

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2 shared papersGenomics

Karen AdelmanORCID

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3 papers

Recent·Most cited

GenomicsNature CommunicationsPeer-reviewedJul 11, 2019

NF-Y Controls Fidelity of Transcription Initiation at Gene Promoters Through Maintenance of the Nucleosome-Depleted Region

Andrew Oldfield, Telmo Henriques, Dhirendra Kumar…·Raja Jothi

This study shows NF-Y maintains nucleosome-depleted regions at promoters to ensure accurate transcription initiation, preventing aberrant gene expression.

94 citations

humanChIP-seq

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BioinformaticsJournal of The Royal Society InterfacePeer-reviewedApr 1, 2018

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Opportunities And Obstacles For Deep Learning In Biology And Medicine

Travers H. Ching, Daniel Himmelstein, Brett K. Beaulieu‐Jones…·Casey S. Greene

Deep learning rivals or beats baselines across imaging, health records, genomics and drug discovery but is not yet transformative; scarce labels, privacy and opacity remain hurdles.

2,300 citationstop 1%

humanmultiple species

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Molecular BiologyeLifePeer-reviewedMar 27, 2017

Histone gene replacement reveals a post-transcriptional role for H3K36 in maintaining metazoan transcriptome fidelity

Michael P. Meers, Telmo Henriques, Christopher A. Lavender…·A. Gregory Matera

This study replaces H3K36 with arginine in Drosophila to show H3K36 methylation maintains transcriptome fidelity through post-transcriptional mechanisms involving polyadenylation.

46 citations

Drosophilabulk RNA-seq

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