Telmo Henriques

The paper shows the Integrator complex destabilizes paused RNA polymerase II at promoters, leading to termination of non-productive transcription.

This study shows NF-Y maintains nucleosome-depleted regions at promoters to ensure accurate transcription initiation, preventing aberrant gene expression.

The paper identifies PCIF1 as the first human m6Am methyltransferase and shows it regulates gene expression by suppressing cap-dependent translation through m6Am methylation.

The paper measures splicing rates genome-wide in Drosophila to understand how gene architecture affects splicing efficiency and accuracy.

This study replaces H3K36 with arginine in Drosophila to show H3K36 methylation maintains transcriptome fidelity through post-transcriptional mechanisms involving polyadenylation.