Florian Fournès

Genome replication and cell division control by the methylation-sensitive GcrA regulator in Agrobacterium tumefaciens

This study shows that GcrA, a methylation-dependent regulator in Agrobacterium tumefaciens, controls replication timing and cell division by coordinating RepABC origins and divisome gene expression.

A LexA-like repressor and global H-NS-like regulators enable the fine-tuning of R-tailocin expression in environmental Pseudomonas

The paper identifies regulators that control R-tailocin expression in Pseudomonas protegens CHA0, showing how DNA damage activates these genes through LexA-like and H-NS proteins.

The pathway to resolve dimeric forms distinguishes plasmids from megaplasmids in Enterobacteriaceae

The paper identifies that XerCD recombination is used by large plasmids and chromids for dimer resolution, similar to chromosomes, and shows this is required for their faithful inheritance.

Cassette recombination dynamics within chromosomal integrons are regulated by toxin-antitoxin systems.

The paper shows toxin-antitoxin systems regulate cassette recombination dynamics in chromosomal integrons by killing cells when excision rates are too high.

Cassette recruitment in the chromosomal Integron of Vibrio cholerae

The paper investigates cassette recruitment in the chromosomal integron of Vibrio cholerae during conjugation and natural transformation, showing that horizontally transferred cassettes can be inserted and expressed.