Phase resetting in human stem cell derived cardiomyocytes explains complex cardiac arrhythmias
Khady Diagne, Thomas M. Bury, Morgan E Pettebone, Marc William Deyell, Zachary Laksman, Alvin Shrier, Leon Glass, Gil Bub, Emilia G. Entcheva
The paper uses optogenetic stimulation and computational models to analyze phase resetting in human iPSC-derived cardiomyocytes, showing how it explains cardiac arrhythmias and offers strategies to prevent them.
PLoS Computational Biology · Feb 4, 2026Peer-reviewedPhysiology