Author

Stephanie I. Protze

University Health NetworkORCID 0000-0002-7993-3780Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Bioengineering· 1 Cell Biology· 1 Developmental Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 3 Organism:human· 3 Approach:experimental assay· 2 Assay:scRNA-seq· 2 Assay:bulk RNA-seq· 1 Research Focus:clustering· 1 Research Focus:gene regulatory network inference· 1 Approach:genetic perturbation / CRISPR· 1

Frequent Co-Authors

Brandon M. MurareanuiD· 3 shared Michael A. LaflammeiD· 3 shared Amine MazineiD· 2 shared Amos A. Lim· 2 shared Maggie Kwan· 2 shared Matthew L. ChangiD· 2 shared Michelle Lohbihler· 2 shared Aanshi GandhiiD· 1 shared

Activity by Year

2024-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 30 mutual co-author links

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3 shared papersDevelopmental Biology

Brandon M. MurareanuORCID

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3 papers

Recent·Most cited

Human pluripotent stem cell-derived atrioventricular node-like pacemaker cells exhibit biological conduction bridge properties in vitro and in vivo

Michelle Lohbihler, Amos A. Lim, Stéphane Massé, Maggie Kwan, Omar Mourad, Olya Mastikhina, Brandon M. Murareanu, Malak Elbatarny, Renu Sarao, Beiping Qiang, Wahiba Dhahri, Matthew L. Chang, Alice L.Y. Xu, Amine Mazine, Shahryar Khattak, , Stephanie I. Protze

This study generates human pluripotent stem cell-derived AVN-like pacemaker cells that replicate AVN function in vivo, suggesting their potential as biological conduction bridges for treating AV block.

bioRxiv · Sep 4, 2025 · PreprintDevelopmental Biology

Single-cell transcriptome analysis reveals CD34 as a novel marker of human sinoatrial node pacemaker cardiomyocytes

Amos A. Lim, Delaram Pouyabahar, Mishal Ashraf, Kate Huang, Michelle Lohbihler, Brandon M. Murareanu, Matthew L. Chang, Maggie Kwan, Faisal J. Alibhai, Thinh Huy Tran, Amine Mazine, Michael A. Laflamme, Gary D. Bader, Zachary Laksman, Stephanie I. Protze

Nature Communications · Nov 27, 2024Peer-reviewedCell Biology

FAST-STEM: A human pluripotent stem cell engineering toolkit for rapid design-build-test-learn development of human cell-based therapeutic devices

Aaron H. Rosenstein, Rangarajan Sambathkumar, Brandon M. Murareanu, Navroop K. Dhaliwal, Fumao Sun, Xinyaun Zhao, Abolfazl Dadvar, Rasha Al-attar, Andrew Chai, Nitya Gulati, Ting Yin, Maria Nguyen, Danielle Serra, Tania Devina, Aanshi Gandhi, , Michael Garton

FAST-STEM accelerates human pluripotent stem cell engineering by enabling rapid transgene integration and differentiation into multiple cell types.

bioRxiv · May 23, 2024 · PreprintBioengineering