Author

Caroline M. Alexander

University of Wisconsin–MadisonORCID 0000-0002-7830-8043Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cancer Biology· 1 Molecular Biology· 1 Physiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Organism:human· 2 Assay:proteomics· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell-cell communication· 1 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

Adam J. KuchniaiD· 1 shared Alexander NassariD· 1 shared Andrea GalmozziiD· 1 shared Annie JeniD· 1 shared Avtar RoopraiD· 1 shared Cameron J. Kaminsky· 1 shared Celia M. BisbachiD· 1 shared Chi–Liang Eric YeniD· 1 shared

Activity by Year

2022-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 18 mutual co-author links

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1 shared paperCancer Biology

Adam J. KuchniaORCID

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3 papers

Recent·Most cited

Tumor-Derived Polyamines Initiate Fat Wasting in Cancer Cachexia

Matías Fabregat, Rachel J. Fenske, Julia K. Hansen, Cameron J. Kaminsky, Jevin Jay Lortie, Alexander Nassar, Kaitlin A. Kressin, Annie Jen, Lucia Cilloni, Katherine A. Overmyer, Caroline M. Alexander, John W. Garrett, Perry Joseph Pickhardt, Joshua J. Coon, Costas Andreas Lyssiotis, , Andrea Galmozzi

This study identifies polyamine-dependent tumor-adipose crosstalk as an early driver of fat wasting in cancer cachexia, linking polyamine metabolism to adipocyte lipolysis and poor patient survival.

bioRxiv · Dec 3, 2025 · PreprintCancer Biology

Dietary lipid is largely deposited in skin and rapidly affects insulating properties

Nick Riley, Ildikó Kasza, Isabel D. K. Hermsmeyer, Michaela E. Trautman, Greg Barrett-Wilt, Raghav Jain, Judith A. Simcox, Chi–Liang Eric Yen, Ormond A. MacDougald, Dudley W. Lamming, Caroline M. Alexander

The paper shows dietary lipid is deposited in skin, altering its thermal properties and energy regulation within days.

Nature Communications · May 16, 2025Peer-reviewedPhysiology

Enhanced Immunoprecipitation Techniques for the Identification of RNA Binding Protein Partners: CRD-BP interactions in mammary epithelial cells

Saja A. Fakhraldeen, Scott Michael Berry, David J. Beebe, Avtar Roopra, Celia M. Bisbach, Vladimir S. Spiegelman, Natalie M. Niemi, Caroline M. Alexander

The paper introduces exclusion-based immunoprecipitation methods to identify RNA binding partners of CRD-BP in mammary epithelial cells, showing enrichment in mRNAs related to mitochondrial function and oxidative stress.

Journal of Biological Chemistry · Jan 29, 2022Peer-reviewedMolecular Biology