Author

Marc Graille

Centre National de la Recherche ScientifiqueORCID 0000-0002-7853-5852Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Biochemistry· 2 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:yeast· 3 Research Focus:cell signaling & trafficking· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1 Assay:structural biology· 1

Frequent Co-Authors

Cosmin SaveanuiD· 2 shared Hervé Le HiriD· 2 shared Irène Barbarin-BocahuiD· 2 shared Mouna Raji· 2 shared Nadia Ruiz-GutierreziD· 2 shared Nathalie UlryckiD· 2 shared Amandine Rigobert· 1 shared Bastien MorletiD· 1 shared

Activity by Year

2024-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

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2 shared papersBiochemistry

Cosmin SaveanuORCID

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3 papers

Recent·Most cited

Molecular BiologybioRxivPreprintOct 29, 2026

Pho92 direct interaction with Not1 recruits the CCR4-NOT complex to m6A containing mRNAs to modulate meiosis in S. cerevisiae

Lina Sene, Ditipriya Hazra, Jérémy Scutenaire…·Marc Graille

This study shows Pho92 interacts with Not1 to recruit the CCR4-NOT complex to m6A-containing mRNAs, modulating meiosis in S. cerevisiae.

DOI 10.64898/2026.10.27.762167

yeastexperimental assay

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BiochemistryNucleic Acids ResearchPeer-reviewedFeb 18, 2025

Mapping interactions within the NMD decapping complex reveals how Upf1 recruits Dcp2 onto mRNA targets

Nadia Ruiz-Gutierrez, Jeanne Dupas, Elvire Auquier…·Hervé Le Hir

The paper maps interactions within the NMD decapping complex, showing how Upf1 recruits Dcp2 onto mRNA targets through domain-specific binding and competition.

6 citations

yeastexperimental assay

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BiochemistryPLoS BiologyPeer-reviewedSep 27, 2024

Identification of an evolutionary conserved binding motif responsible for the recruitment of NMD factors to the UPF1 helicase

Irène Barbarin-Bocahu, Nathalie Ulryck, Amandine Rigobert…·Marc Graille

The paper identifies a conserved binding motif in Nmd4 that interacts with Upf1, showing its role in NMD and conservation in metazoan SMG6.

6 citations

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