This study investigates sex-specific stress responses to acute and chronic social defeat stress, finding differences in behavioral outcomes between males and females.

bioRxiv · Oct 1, 2026 · PreprintNeuroscience

Microglial Fructose Metabolism Is Essential for Glioblastoma Growth

Leah K. Billingham, Susan L DeLay, Yasmina Eshac, Tzu-Yi Chia, Shashwat Tripathi, Ian E Olson, Kaylee Zilinger, Jay Subbiah, Zhaoquan Wang, Nishanth S. Sadagopan, Hinda Najem, Guillaume Cognet, Joshua L. Katz, Ruochen Du, Khizar Rehan Nandoliya, , Jason M. Miska

This study shows that microglial fructose metabolism via GLUT5 is critical for glioblastoma growth, as GLUT5-KO mice live longer with reduced tumor progression.

Proceedings of the National Academy of Sciences · Mar 17, 2026Peer-reviewedCancer Biology

A Novel Localized Tracing Technique to Explore Intra-Amygdala Functional and Structural Connectivity Patterns as Mediators of Individual Variability in Stress Response

Allie B. Lipshutz, Victoria Saltz, Kristin R Anderson, Alessia Manganaro, Dani Dumitriu

The paper develops a novel tracing technique to investigate intra-amygdala connectivity patterns as predictors of individual variability in stress responses, identifying potential biological markers for trait vulnerability.

bioRxiv · Nov 29, 2022 · PreprintNeuroscience

Maternal separation affects fronto-cortical activity in rat pups during dam-pup interactions and behavioral transitions

Manon Ranger, Tatyana B. Behring, Jasmine H. Kaidbey, Muhammad Anwar, Allie B. Lipshutz, Isabelle Mollicone, Gehad Hassan, Kathryn Mayring Fasano, Nicole K. Hinz, Robert J. Ludwig, Michael M. Myers, Martha G. Welch, Dani Dumitriu

This study shows that maternal separation in rat pups reduces frontal cortex EEG power during dam-pup interactions, suggesting a link between early-life stress and neurodevelopmental impacts.

bioRxiv · May 19, 2021 · PreprintNeuroscience