Qi Liu

Self-supervised learning for a gene program-centric view of cell states

Tripso, a self-supervised transformer model, identifies gene program-specific embeddings and discovers novel gene programs, revealing biological insights in hematopoietic development and disease.

ADAT2/3-mediated tRNA editing promotes cancer cell growth and tumorigenicity

This study shows that ADAT2/3-mediated tRNA editing supports cancer cell growth and tumorigenicity by enhancing translation of growth-promoting mRNAs.

Identifying Lineage-specific Targets of Darwinian Selection by a Bayesian Analysis of Genomic Polymorphisms and Divergence from Multiple Species

The paper introduces a Bayesian method to detect lineage-specific selection in multiple species and identifies new genes under selection in Hominidae evolution.

AIM-SNPtag: a computationally efficient approach for developing ancestry-informative SNP panels

The paper develops a computational method to create ancestry-informative SNP panels with high accuracy and small size, outperforming existing methods in multiple population groups.