Richard I. Gregory

This study identifies tRNA-Arg-TCT-4-1 as a new anti-cancer therapeutic target and shows that targeting it with an ASO suppresses tumorigenesis and extends survival in mouse models.

This study shows that ADAT2/3-mediated tRNA editing supports cancer cell growth and tumorigenicity by enhancing translation of growth-promoting mRNAs.

The paper identifies a pre-tRNA decay pathway mediated by EXOSC10 that is critical for neuron survival and linked to neurodevelopmental disorders.

This study shows that RNA methylation, specifically m6A, regulates stress granule formation and function during erythropoiesis by modulating ATXN2 expression and RNA translation.

This paper introduces EpiPlex, a method for simultaneous mapping of multiple RNA modifications, demonstrating its application in analyzing m6A and inosine levels in HEK293T cells.