Dietary L-3,4-dihydroxyphenylalanine (L-DOPA) augments cuticular melanization in Anopheles mosquitos while reducing their lifespan and malaria parasite burden
Emma Camacho, Yuemei Dong, Christine Chrissian, Radamés J. B. Cordero, Raúl G. Saraiva, Yesseinia Angleró-Rodríguez, Daniel F. Q. Smith, Ella Jacobs, Isabella Hartshorn, José Alberto Patiño-Medina, Michael DePasquale, Amanda Dziedzic, Anne Jedlicka, Barbara Smith, Godfree Mlambo, , Arturo Casadevall
This study shows dietary L-DOPA increases melanization, immunity, and reduces lifespan in Anopheles mosquitoes, while lowering malaria parasite burden.
Nature Communications · Aug 27, 2025Peer-reviewedMicrobiology