Author

Godfree Mlambo

Johns Hopkins UniversityORCID 0000-0001-8917-9710Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:host-pathogen & immune response· 2 Organism:plant (other)· 2 Assay:DNA methylation· 1 Research Focus:gene regulatory network inference· 1 Organism:human· 1 Organism:multiple species· 1 Approach:statistical model· 1

Frequent Co-Authors

Abhai K. TripathiiD· 3 shared Photini SinnisiD· 3 shared Sachel MokiD· 3 shared Anne‐Catrin UhlemanniD· 2 shared David A. FidockiD· 2 shared Eva Gil‐IturbeiD· 2 shared Felix D. RozenbergiD· 2 shared Filippo ManciaiD· 2 shared

Activity by Year

2023-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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3 shared papersMicrobiology

Abhai K. TripathiORCID

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

A Plasmodium falciparum PX1 haplotype is associated with reduced susceptibility to artemisinin and lumefantrine

Christopher Bower-Lepts, Arvind Jangra, Sachie Kanatani, Abhai Tripathi, Godfree Mlambo, Alejandro McCotter-Gonzalez, Linda Romano, Stephen Orena, Martin Okitwi, Karamoko Niaré, Philip Joseph Rosenthal, Melissa D. Conrad, Photini Sinnis, Sachel Mok

This study identifies a PX1 haplotype in Plasmodium falciparum associated with reduced susceptibility to artemisinin and lumefantrine, providing a marker for drug resistance surveillance.

bioRxiv · Sep 9, 2026 · PreprintMicrobiology

Dietary L-3,4-dihydroxyphenylalanine (L-DOPA) augments cuticular melanization in Anopheles mosquitos while reducing their lifespan and malaria parasite burden

Emma Camacho, Yuemei Dong, Christine Chrissian, Radamés J. B. Cordero, Raúl G. Saraiva, Yesseinia Angleró-Rodríguez, Daniel F. Q. Smith, Ella Jacobs, Isabella Hartshorn, José Alberto Patiño-Medina, Michael DePasquale, Amanda Dziedzic, Anne Jedlicka, Barbara Smith, Godfree Mlambo, , Arturo Casadevall

This study shows dietary L-DOPA increases melanization, immunity, and reduces lifespan in Anopheles mosquitoes, while lowering malaria parasite burden.

Nature Communications · Aug 27, 2025Peer-reviewedMicrobiology

Plasmodium falciparum quinine resistance is multifactorial and includes a role for the drug/metabolite transporters PfCRT and DMT1

Mariko Kanai, Sachel Mok, Tomas Yeo, Melanie J. Shears, Jin H. Jeon, Sunil Kumar Narwal, Leila Saxby Ross, Meseret T. Haile, Abhai K. Tripathi, Godfree Mlambo, Jonathan Kim, Eva Gil‐Iturbe, John Okombo, Heekuk Park, Kharizta Wiradiputri, , David A. Fidock

This study identifies DMT1 and a chromosome 12 locus, including FtsH1, as novel contributors to Plasmodium falciparum resistance to quinine, alongside the known pfcrt gene.

bioRxiv · Sep 27, 2024 · PreprintGenetics

Mapping the genomic landscape of multidrug resistance in Plasmodium falciparum and its impact on parasite fitness

Sachel Mok, Tomas Yeo, Davin Hong, Melanie J. Shears, Leila Saxby Ross, Kurt E. Ward, Satish K. Dhingra, Mariko Kanai, Jessica L. Bridgford, Abhai K. Tripathi, Godfree Mlambo, Anna Y. Burkhard, Megan R. Ansbro, Kate J. Fairhurst, Eva Gil‐Iturbe, , David A. Fidock

The paper identifies genetic determinants of multidrug resistance in Plasmodium falciparum and their impact on parasite fitness and drug susceptibility.

Science Advances · Nov 8, 2023Peer-reviewedGenomics