Suzanne J. F. Kaptein

This study characterizes the multiphasic viral replication kinetics of rat HEV in vivo, showing liver as the main replication site and ribavirin's partial efficacy in preventing viral rebound.

This study shows that Oropouche virus causes severe congenital malformations and neurodevelopmental issues in embryonic mice, mirroring human fetal cases.

This study establishes an HEV-HIE model showing HEV replication in intestinal epithelial cells, with proliferative cells being the main targets, suggesting the gut as an HEV reservoir.

The paper identifies orally bioavailable inhibitors of the Zika virus NS2B-NS3 protease that show antiviral activity in vitro and reduce viral RNA load in a murine infection model.

The paper describes the development of a broadly neutralizing antibody, XVR011, effective against SARS-CoV-2 and its variants in animal models.