Proximity labeling of the Tau repeat domain enriches RNA-binding proteins that are altered in Alzheimer's disease and related tauopathies
Sarah M. Shapley, Anantharaman Shantaraman, Joshna Dharmendrabhai Gadhavi, Masin A. Kearney, Eric B. Dammer, Duc M. Duong, Christine A Bowen, Caroline M Watson, Pritha Bagchi, Qi Guo, Srikant Rangaraju, Nicholas T. Seyfried
The paper identifies RNA-binding proteins interacting with tau's repeat domain using proximity labeling, showing their enrichment in Alzheimer's and tauopathies.
Molecular & Cellular Proteomics · Nov 7, 2025Peer-reviewedNeuroscience