Paulina Pilanc

The paper integrates spatial transcriptomics with immunofluorescence to study astrocyte heterogeneity and function in glioblastomas, revealing spatial distribution and interactions within the tumor microenvironment.

This study shows that an integrin-blocking peptide enhances anti-PD-1 therapy in gliomas by reversing immunosuppression and restoring an inflammatory tumor microenvironment.

This paper develops a deep learning model for glioma grading using a tumor microenvironment analysis protocol, achieving 0.85 accuracy on a small, imbalanced dataset with single-stained biopsies.