Thomas Andrew Longden

This study shows that Gαq/11 signaling in brain endothelial cells prevents endothelial dysfunction and cognitive decline in aged mice by maintaining vascular reactivity and preventing blood-brain barrier disruption.

SALM uses deep learning to convert motion-blurred streaks into high-resolution brain imaging, reducing reconstruction time and enabling scalable, cross-platform applications.

This study identifies capillary pericytes as metabolic sentinels that increase blood flow in response to glucose depletion through KATP channel activation.

The paper identifies P2Y2 receptors in RTN vascular smooth muscle cells as essential for CO2/H+ chemoreception and respiratory behavior in mice.