Author

Hamed Khalili

Massachusetts General HospitalORCID 0000-0002-7956-6941Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Genetic & Genomic Medicine· 2 Genetics· 1 Genomics· 1

Signature Assays, Organisms & Methods

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Organism:human· 4 Approach:statistical model· 3 Research Focus:GWAS / association mapping· 2 Assay:bulk RNA-seq· 1 Research Focus:eQTL / molecular QTL mapping· 1 Research Focus:fine-mapping· 1 Assay:whole-exome sequencing· 1 Assay:whole-genome sequencing· 1

Frequent Co-Authors

Ashwin N. AnanthakrishnaniD· 3 shared Aarno V. PalotieiD· 2 shared Andrew Tan ChaniD· 2 shared Daniel B. GrahamiD· 2 shared Jeffrey C. BarrettiD· 2 shared Mark J. DalyiD· 2 shared Ramnik J. XavieriD· 2 shared Stacey GabrieliD· 2 shared

Activity by Year

2018-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 27 mutual co-author links

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Curved chords = mutual co-authorship

3 shared papersGenetic & Genomic Medicine

Ashwin N. AnanthakrishnanORCID

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Author profile →

4 papers

Recent·Most cited

Mapping the dynamic genetic regulatory architecture of HLA genes at single-cell resolution

Joyce B. Kang, Amber Z. Shen, Saisriram Gurajala, Aparna Nathan, Laurie Rumker, Vitor R. C. Aguiar, Cristian Valencia, Kaitlyn A. Lagattuta, Fan Zhang, Anna Helena Jonsson, Seyhan Yazar, José Alquicira-Hernández, Hamed Khalili, Ashwin N. Ananthakrishnan, Karthik A. Jagadeesh, , Joseph E. Powell

The paper maps cell-type-specific eQTLs for HLA genes across multiple tissues and identifies dynamic regulation of HLA-DQ genes in immune cells.

Nature Genetics · Nov 30, 2023Peer-reviewedGenetic & Genomic Medicine

Sequencing of over 100,000 individuals identifies multiple genes and rare variants associated with Crohns disease susceptibility

Aleksejs Sazonovs, Christine R. Stevens, Guhan Ram Venkataraman, Kai Yuan, Brandon E. Avila, Maria T. Abreu, Tariq Ahmad, Matthieu Allez, Ashwin N. Ananthakrishnan, Gil Atzmon, Aris Baras, Jeffrey C. Barrett, Nir Barzilai, Laurent Beaugerie, Ashley Harris Beecham, , Rasha Shawky

The paper identifies ten new genes with coding variants linked to Crohn's disease risk using sequencing data from over 30,000 patients and 80,000 controls.

Nature Genetics · Aug 29, 2022Peer-reviewedGenetic & Genomic Medicine

Rewiring of the cellular and inter-cellular landscape of the human colon during ulcerative colitis

Christopher S. Smillie, Moshe Biton, José Ordovás-Montañés, Keri M. Sullivan, Grace Burgin, Daniel B. Graham, Rebecca H. Herbst, Noga Rogel, Michal Slyper, Julia Waldman, Malika Sud, Elizabeth Andrews, Adam L. Haber, Sanja Vicković, Danielle Ashley Dionne, , Aviv Regev

The paper was withdrawn due to the inclusion of confidential information about a third party.

bioRxiv · May 25, 2019 · PreprintGenomics

Narrow-sense heritability estimation of complex traits using identity-by-descent information.

Luke M. Evans, Rasool Tahmasbi, Matthew Jones, Scott I. Vrieze, Gonçalo R. Abecasis, Sayantan Das, Douglas W. Bjelland, Teresa R de Candia, David Altshuler, Carl A. Anderson, Andrea Angius, Jeffrey C. Barrett, Sonja I. Berndt, Michael Boehnke, Dorrett Boomsma, , George Davey Smith

This paper estimates narrow-sense heritability using identity-by-descent information in unrelated individuals and finds that IBD-based methods can capture rare variant contributions but are affected by stratification.

Heredity · Mar 28, 2018Peer-reviewedGenetics