Jean‐Léon Thomas

The paper shows that activating RIG-I in macrophages enhances immunotherapy for glioblastoma by repolarizing tumor-associated macrophages and boosting anti-tumor immune responses.

This study shows that dural venous stenoses impair lymphatic drainage and brain fluid clearance, and that restoring venous flow can improve clearance in a mouse model.

This study shows that VEGF-C overexpression enhances brain fluid drainage, provides neuroprotection, and improves stroke outcomes in mice.

The paper uses 3D imaging to study the vascular development of the mouse epididymis, revealing the organization of blood and lymphatic networks during development.

This study shows that Cx43-mediated interactions between neural stem cells and endothelial cells in the SVZ regulate NSC quiescence and neurogenesis.

The paper establishes the 3D anatomy of meningeal lymphatic vasculature and CSF drainage in mice and humans using imaging techniques, showing conserved lymphatic structures.

The paper uses whole-genome and RNA sequencing from the human prefrontal cortex to identify genetic variants and transcriptomic changes associated with neurodevelopment and neuropsychiatric disorders.