Author

Luiz Henrique Geraldo

InsermORCID 0000-0003-3318-4697Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Organism:mouse· 4 Approach:experimental assay· 3 Organism:human· 3 Assay:bulk RNA-seq· 2 Research Focus:differential expression· 2 Approach:statistical model· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1

Frequent Co-Authors

Amanda W. LundiD· 2 shared Anne EichmanniD· 2 shared Irineu Illa Bochaca· 2 shared Jean‐Léon ThomasiD· 2 shared Marie-Renée El KamouhiD· 2 shared Myriam SpajeriD· 2 shared Alec C. KimmelmaniD· 1 shared Alec P. BreazealeiD· 1 shared

Activity by Year

2022-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 17 mutual co-author links

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2 shared papersCancer Biology

Amanda W. LundORCID

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Cross-species spatial profiling links progranulin to an immune suppressive niche in brain metastasis

Nicole M. Eskow, Kylie Prutisto-Chang, María A. Gómez-Muñoz, Minkyung Kang, Irineu Illa Bochaca, Milad Ibrahim, Sorin A. A. Shadaloey, Amanda Flores Yanke, Luiz Henrique Geraldo, Giuseppe Barisano, Anuja Sathe, Pablo Nunez Perez, David A. Solomon, Elif Tugce Karasu, Hanlee P. Ji, , Eva Hernando

The paper identifies progranulin as a mediator of immune suppressive niches in brain metastasis using cross-species spatial transcriptomics and functional analyses.

bioRxiv · Sep 19, 2026 · PreprintCancer Biology

IFNγ-dependent metabolic reprogramming restrains an immature, pro-metastatic lymphatic state in melanoma

Triantafyllia R. Karakousi, Vanessa Cristaldi, Maria Luiza Lopes de Oliveira, Ines Delclaux, Naomi R. Besson, Luiz Henrique Geraldo, Tania J González-Robles, Devyon R. McDonnough, Daniel Martinez-Krams, Gabrielle Silva, Alec P. Breazeale, Joel Encarnación-Rosado, Joanna Poźniak, Shi Qiu, Irineu Illa Bochaca, , Amanda W. Lund

This study shows that IFNγ suppresses lymphatic vessel growth and metastasis by altering metabolism and immune function in melanoma.

Cancer Cell · Jan 22, 2026Peer-reviewedCancer Biology

VEGF-C promotes brain-derived fluid drainage, confers neuroprotection, and improves stroke outcomes

Lígia Simões Braga Boisserand, Jean Bouchart, Luiz Henrique Geraldo, Seyoung Lee, Basavaraju G. Sanganahalli, Maxime J. Parent, Shenqi Zhang, Yuechuan Xue, Mario Škarica, Justine Guégan, Mingfeng Li, Xiodan Liu, Mathilde Poulet, Michael Askanase, Artem Osherov, , Jean‐Léon Thomas

This study shows that VEGF-C overexpression enhances brain fluid drainage, provides neuroprotection, and improves stroke outcomes in mice.

bioRxiv · May 30, 2023 · PreprintNeuroscience

3D-imaging reveals conserved cerebrospinal fluid drainage via meningeal lymphatic vasculature in mice and humans

Laurent Jacob, José M. Brito, Stéphanie Lenck, Céline Corcy, Farhat Benbelkacem, Luiz Henrique Geraldo, Yunling Xu, Jean-Mickael Thomas, Marie-Renée El Kamouh, Myriam Spajer, Marie‐Claude Potier, Stéphane Haı̈k, Michel Kalamarides, Bruno Stankoff, Stéphane Lehéricy, , Jean‐Léon Thomas

The paper establishes the 3D anatomy of meningeal lymphatic vasculature and CSF drainage in mice and humans using imaging techniques, showing conserved lymphatic structures.

The Journal of Experimental Medicine · Jun 9, 2022Peer-reviewedNeuroscience