James A. Bourne

Robust and accessible in situ sequencing with an open-source automated sequencer

The paper introduces Seq-o-Matic, an open-source automated in situ sequencer that reduces hands-on time and improves sequencing consistency across tissue sections.

Early-life medial pulvinar disruption drives schizophrenia-relevant prefrontal inhibitory and cognitive deficits in primates

This study shows that early-life disruption of the medial pulvinar in marmosets leads to adult prefrontal inhibitory and cognitive deficits relevant to schizophrenia.

Conserved and specialized features of thalamocortical wiring revealed by single-cell projection mapping in mouse and marmoset

The paper uses single-cell projection mapping in mice and marmosets to show that thalamocortical projections are spatially segregated in marmosets but follow a conserved gradient in both species.

Widespread Corticothalamic Connectivity Identifies the Inferior Pulvinar as a Central Node in Visual Network Architecture

This study maps the cortical inputs to the inferior pulvinar in marmosets, revealing its role as a central integrative node in visual and visuomotor networks.

Dynamic fibroblast-immune interactions shape wound healing after brain injury

This study identifies dynamic fibroblast-immune interactions that regulate CNS wound healing and neuroinflammation after brain injury.

CalliCog: an open-source cognitive neuroscience toolkit for freely behaving nonhuman primates

CalliCog enables automated cognitive experiments in freely behaving marmosets, achieving touchscreen proficiency within two weeks and integrating with ECoG recordings.

Developmental dynamics of the prefrontal cortical SST and PV interneuron networks: Insights from the monkey highlight human-specific features

This study examines the developmental dynamics of PV and SST interneurons in marmoset monkeys, revealing prolonged PV maturation and reduced SST numbers compared to rodents.

Visual Cortical Area MT is Required For Development of the Dorsal Stream and Associated Visuomotor Behaviours

This study shows that early-life loss of visual area MT causes anatomical, physiological, and behavioural changes in primate vision and motor functions.

Mapping the neural circuitry of predator fear in the nonhuman primate

The paper investigates whether a conserved brain network involved in predator fear in rodents is also active in nonhuman primates during visually evoked predator fear.

Replicating infant astrocyte behavior in the adult after brain injury improves outcomes

The paper shows that reintroducing ephrin-A1 in adults after brain injury mimics infant neuroprotective mechanisms, reducing glial scarring and improving neuronal survival.

Primate-specific response of astrocytes to stroke limits peripheral macrophage infiltration

The paper identifies primate-specific astrocyte responses to stroke, showing NogoA limits macrophage infiltration and suggests therapeutic targeting.

A Hox code defines spinocerebellar neuron subtype regionalisation

The paper identifies a Hox code that defines molecular regionalisation of spinocerebellar neuron subtypes in the cervico-thoracic spinal cord.