Miglė Gabrielaitė

Thirty years of Achromobacter ruhlandii evolution reveal pathways to epidemic lineages

This study analyzes the evolution of Achromobacter ruhlandii over 30 years, identifying genomic features associated with epidemic potential and chronic infections.

Whole-genome DNA methylation profiling in COVID-19 positive patients reveals alterations in pathways linked to neurological dysfunction

This study profiles DNA methylation in COVID-19 patients and finds hypomethylation linked to neurological pathways in severe cases.

A comparison of tools for copy-number variation detection in germline whole exome and whole genome sequencing data

The paper benchmarks CNV detection tools on WGS and WES data using clinical standards and reference samples, finding that combining multiple tools improves recall but precision remains a challenge.

Transmission and antibiotic resistance of Achromobacter in cystic fibrosis

The paper analyzes Achromobacter infections in cystic fibrosis patients using whole-genome sequencing to identify transmission patterns and antibiotic resistance development.

GenAPI: a tool for gene absence-presence identification in fragmented bacterial genome sequences

GenAPI identifies gene absence-presence in fragmented bacterial genomes, showing high sensitivity and precision compared to existing tools.