Author

Juan R. Del Valle

University of Notre DameORCID 0000-0002-7964-8402Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 2 Approach:experimental assay· 2 Research Focus:cell-cell communication· 1 Research Focus:protein folding & dynamics· 1 Research Focus:synaptic & neural circuits· 1

Frequent Co-Authors

Alex TongiD· 1 shared Benjamin H. RajewskiiD· 1 shared Carlos BustamanteiD· 1 shared Daniel G. GuerraiD· 1 shared Gaeun KimiD· 1 shared Isaac J. AngeraiD· 1 shared Omar Herrera-AsmatiD· 1 shared Richard H. EbrightiD· 1 shared

Activity by Year

2025-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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1 shared paperBiophysics

Alex TongORCID

Mutual co-authors in cluster

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2 papers

Recent·Most cited

Pleomorphic effects of three small-molecule inhibitors on transcription elongation by Mycobacterium tuberculosis RNA polymerase

Omar Herrera-Asmat, Alex Tong, Wenxia Lin, Tiantian Kong, Juan R. Del Valle, Daniel G. Guerra, Yon W. Ebright, Richard H. Ebright, Carlos Bustamante

This study characterizes the effects of three small-molecule inhibitors on MtbRNAP transcription elongation using optical tweezers, revealing distinct inhibition mechanisms and synergistic effects.

eLife · Oct 3, 2025Peer-reviewedBiophysics

N-Amino Peptide-Graphene Quantum Dot Loaded Small Extracellular Vesicles for Targeted Therapy of Tauopathies

Runyao Zhu, Gaeun Kim, Benjamin H. Rajewski, Isaac J. Angera, Juan R. Del Valle, Yichun Wang

This study develops N-Amino Peptide-Graphene Quantum Dot loaded small extracellular vesicles to target tauopathies, showing improved specificity and efficacy in inhibiting tau aggregation and transmission.

Advanced NanoBiomed Research · Jul 22, 2025Peer-reviewedBioengineering