Author

Sili Fan

University of California, DavisORCID 0000-0002-3497-1695Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Bioinformatics· 1 Genetics· 1 Neuroscience· 1 Systems Biology· 1

Signature Assays, Organisms & Methods

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Approach:statistical model· 4 Assay:metabolomics· 3 Research Focus:differential expression· 2 Organism:human· 2 Organism:mouse· 2 Assay:bulk RNA-seq· 1 Research Focus:database / resource· 1 Approach:experimental assay· 1

Frequent Co-Authors

Dinesh Kumar BarupaliD· 3 shared Oliver FiehniD· 3 shared Arpana Vaniya· 2 shared Tobias KindiD· 2 shared Alzheimer’s Disease Neuroimaging Initiative· 1 shared Amber L. BeitelsheesiD· 1 shared Amit PatkiiD· 1 shared Andrew J. SaykiniD· 1 shared

Activity by Year

2019-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 22 mutual co-author links

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3 shared papersGenetics

Dinesh Kumar BarupalORCID

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Lipid metabolism drives allele-specific early-stage hypertrophic cardiomyopathy

Arpana Vaniya, Anja Karlstaedt, Damla Ates Gulkok, Tilo Thottakara, Yamin Liu, Sili Fan, Hannah Eades, Ryuya Fukunaga, Hilary J. Vernon, Oliver Fiehn, Maria Roselle Abraham

This study identifies allele-specific metabolic differences in HCM mouse models, linking lipid metabolism to early-stage cardiac dysfunction.

bioRxiv · Nov 10, 2023 · PreprintSystems Biology

Leveraging a founder population to identify novel rare-population genetic determinants of lipidome

May E. Montasser, Stella W. Aslibekyan, Vinodh Srinivasasainagendra, Hemant K. Tiwari, Amit Patki, Minoo Bagheri, Tobias Kind, Dinesh Kumar Barupal, Sili Fan, James A. Perry, Kathleen A. Ryan, Donna K. Arnett, Amber L. Beitelshees, Marguerite R. Irvin, Jeffrey R. O’Connell

The paper identifies novel genetic determinants of lipidome variation in a founder population, highlighting rare alleles associated with specific lipid species and replicating known common loci.

bioRxiv · May 21, 2021 · PreprintGenetics

A comprehensive plasma metabolomics dataset for a cohort of mouse knockouts within the international mouse phenotyping consortium

Dinesh Kumar Barupal, Ying Zhang, Tong Shen, Sili Fan, Bryan S. Roberts, Patrick Fitzgerald, Benjamin Wancewicz, Luis Valdiviez, Gert Wohlgemuth, Gregory Byram, Ying Yng Choy, Bennett D Haffner, Megan Reed Showalter, Arpana Vaniya, Clayton S. Bloszies, , Oliver Fiehn

The paper provides a metabolomics dataset from 30 mouse gene knockouts and wildtypes, identifying 832 metabolites across multiple analytical methods.

Metabolites · May 22, 2019Peer-reviewedBioinformatics

Sets of Co-regulated Serum Lipids are Associated with Alzheimer Disease Pathophysiology

Dinesh Kumar Barupal, Rebecca Bailli, Sili Fan, Andrew J. Saykin, Peter J. Meikle, Matthias Arnold, Kwangsik T. Nho, Oliver Fiehn, Rima F Kaddurah-Daouk, Alzheimer’s Disease Neuroimaging Initiative

The paper identifies lipid sets in blood associated with Alzheimer's disease biomarkers and clinical symptoms using lipidomic profiling in the ADNI1 cohort.

bioRxiv · Feb 18, 2019 · PreprintNeuroscience