Author

Jessica Foster

Children's Hospital of PhiladelphiaORCID 0000-0002-8001-5960Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cancer Biology· 2 Genomics· 1

Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 2 Research Focus:gene regulatory network inference· 2 Organism:human· 2 Approach:statistical model· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:clustering· 1 Approach:deep learning· 1

Frequent Co-Authors

Carl Johannes KoschmanniD· 2 shared Adam C. ResnickiD· 1 shared Adam KrayaiD· 1 shared Aditya LahiriiD· 1 shared Alex SickleriD· 1 shared Ammar S. NaqviiD· 1 shared Andrea TimpanaroiD· 1 shared Andrei Thomas‐TikhonenkoiD· 1 shared

Activity by Year

2025-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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2 shared papersCancer Biology

Carl Johannes KoschmannORCID

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3 papers

Recent·Most cited

Preclinical efficacy of combinatorial B7-H3 CAR T cells and ONC206 against diffuse intrinsic pontine glioma

Andrea Timpanaro, Edward Z. Song, Ryma Toumi, Leonel Elena-Sanchez, Caroline Piccand, Kelsey Marie Nemec, Anja Kordowski, Davina Lau, Scott Johnson, Lily I. Winter, Ashmitha Rajendran, Rebecca J. Ronsley, Shannon K. Oda, Joshua A. Gustafson, Jason Wendler, , Nicholas Alexander Vitanza

This paper evaluates the combination of B7-H3 CAR T cells and ONC206 against DIPG models, showing enhanced anti-tumor efficacy in vitro and in vivo.

Neuro-Oncology · Jan 30, 2026Peer-reviewedCancer Biology

Alternative splicing in pediatric central nervous system tumors highlights oncofetal candidate CLK1 exon 4

Ammar S. Naqvi, Patricia J. Sullivan, Ryan J. Corbett, Priyanka D. Sehgal, Karina L. Conkrite, Komal S. Rathi, Brian Ennis, Katharina E. Hayer, Bo Zhang, Miguel Brown, Daniel P. Miller, Alex Sickler, Adam Kraya, Kaleem Coleman, Joseph M. Dybas, , Jo Lynne Rokita

The paper analyzes splicing in 729 pediatric brain tumors, identifies splicing-defined subgroups, and highlights CLK1 exon 4 as an oncofetal event linked to tumor prognosis.

Neuro-Oncology Pediatrics · Jan 1, 2026Peer-reviewedGenomics

A Tonic Signaling Code Predicts CAR-T Cell Efficacy in Diffuse Midline Glioma

Emily Deng, Xiaowen Zhong, Dazhuan Eric Xin, Upendra Kumar Soni, Wenkun Ma, Xiao Huang, Mingjun Cai, Po-Yu Liang, Jun Bai, Qian Qin, Shreya V. Mishra, Ming Hu, Arman Esshaghi Bayat, Jiajie Diao, Mei Xin, , Q. Richard Lu

This study identifies tonic signaling as a key factor in CAR-T cell efficacy for diffuse midline glioma, showing that restrained tonic signaling improves therapeutic outcomes.

bioRxiv · Sep 29, 2025 · PreprintCancer Biology