Author

Matt R. Kelley

Pfizer (United States)ORCID 0000-0002-8010-6328Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Neuroscience· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:cell type annotation· 1 Assay:electronic health records· 1 Organism:human· 1 Organism:mouse· 1

Frequent Co-Authors

Allison P. BergiD· 1 shared Catherine ChoiiD· 1 shared Christopher E. Bope· 1 shared Georgina KontouiD· 1 shared Jack H. HowdeniD· 1 shared Jake S. Dengler· 1 shared Josef T. KittleriD· 1 shared Josephine NgiD· 1 shared

Activity by Year

2021-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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1 shared paperNeuroscience

Allison P. BergORCID

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2 papers

Recent·Most cited

Potentiating NaV1.1 in Dravet syndrome patient iPSC-derived GABAergic neurons increases neuronal firing frequency and decreases network synchrony

Matt R. Kelley, Laura B. Chipman, Shoh M. Asano, Matthew Knott, Samantha Howard, Allison P. Berg

This study shows that enhancing NaV1.1 in Dravet syndrome patient neurons increases firing rates and reduces network synchrony using HD-MEAs.

bioRxiv · Sep 28, 2023 · PreprintNeuroscience

KCC2 is required for the survival of mature neurons but not for their development

Georgina Kontou, Josephine Ng, Ross A. Cardarelli, Jack H. Howden, Catherine Choi, Qiu Ren, Miguel A. Rodriguez Santos, Christopher E. Bope, Jake S. Dengler, Matt R. Kelley, Paul A Davies, Josef T. Kittler, Nicholas J. Brandon, Stephen J. Moss, Joshua L. Smalley

This study shows that KCC2 is essential for the survival of mature neurons but not for their development or structural formation.

Journal of Biological Chemistry · Jan 1, 2021Peer-reviewedNeuroscience