Regulation of cellular LDL uptake by PROX1 and CHD7
Candilianne Serrano-Zayas, Matthew L. Holding, Taslima Gani Khan, Vi T. Tang, Jennifer M. Skidmore, Donna M. Martin, David Ginsburg, Brian T. Emmer
This study identifies PROX1 and CHD7 as regulators of LDL uptake, with PROX1 directly enhancing LDLR expression and CHD7 acting through an LDLR-independent mechanism.
bioRxiv · Sep 20, 2022 · PreprintMolecular Biology