Author

I. Sandra Ndayambaje

Harvard UniversityORCID 0000-0002-8099-2307Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Neuroscience· 2 Cell Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:differential expression· 3 Organism:human· 3 Assay:bulk RNA-seq· 2 Approach:statistical model· 2 Research Focus:cell type annotation· 1 Research Focus:chromatin & epigenetic regulation· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

Michael Emmerson WardiD· 3 shared Aaron HeldiD· 2 shared Ana Rita Agra de Almeida QuadrosiD· 2 shared Brian J. WaingeriD· 2 shared Clotilde Lagier‐TourenneiD· 2 shared Aliza P. WingoiD· 1 shared Amey S. Kavuturu· 1 shared Anantharaman ShantaramaniD· 1 shared

Activity by Year

2022-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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3 shared papersNeuroscience

Michael Emmerson WardORCID

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3 papers

Recent·Most cited

Cell BiologybioRxivPreprintMar 28, 2026

Neurodegeneration risk variants promote lysosomal TMEM106B fibrilaccumulation

John Michael Replogle, Jordan D. Marks, Martin G. Fernandez…·Michael Emmerson Ward

The paper identifies TMEM106B fibril accumulation as a shared mechanism in neurodegeneration linked to genetic variants in TMEM106B and GRN.

3 citations

𝕏 PostBluesky

NeurosciencebioRxivPreprintFeb 24, 2026

Statins and genetic inhibition of the mevalonate pathway activate an ATF3-STMN2 regenerative program

Matthew Nolan, Sandeep Aryal, I. Sandra Ndayambaje…·Clotilde Lagier‐Tourenne

The paper shows statins and mevalonate pathway inhibition increase STMN2 and ATF3, promoting neuronal regeneration in neurodegenerative disease.

1 citation

humanbulk RNA-seq

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NeurosciencebioRxivPreprintOct 25, 2022

iPSC Motor Neurons with Familial ALS Mutations Capture Gene Expression Changes in Postmortem Sporadic ALS Motor Neurons

Aaron Held, Michelle J. Adler, Christine Marques…·Brian J. Wainger

The paper shows iPSC-derived spinal motor neurons with familial ALS mutations capture gene expression changes seen in postmortem sporadic ALS motor neurons, particularly in TDP-43-related splicing dysregulation.

DOI 10.1101/2022.10.25.513780

humanbulk RNA-seq

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